Table 1.
Demographic characteristics and method of UAW sampling of 192 pwCF.
| Nasal lavage according to Mainz | Nasal lavage with rhino-set | Total | |
|---|---|---|---|
| Number (males %) | 88 (54.5%) | 104 (59.6%) | 192 (57.3%) |
| Mean age (years) | 18.1 ± 13.5 | 20.0 ± 13.1 | 19.3 ± 13.6 |
| <8 years (males %) | 16 (50%) | 11 (45.4%) | 27 (48.1%) |
| >8 years (males %) | 71 (54.9%) | 94 (61.7%) | 165 (50.5%) |
| F508del homozygous | 21 | 22 | 43 |
| F508del heterozygous | 38 | 49 | 87 |
| Other genotype | 29 | 33 | 62 |
| ETI treatment at sampling | 3 | 12 | 15 |
| Pancreatic status (insufficiency/sufficiency) | 56/32 | 67/37 | 123/69 |
| BMI kg/m2(mean ± SD) | 19.25 ± 3.76 | 20.20 ± 3.74 | 19.75 ± 3.77 |
| FEV1 % (baseline) (mean ± SD) | 87.21 ± 23.37 | 84.16 ± 23.32 | 85.53 ± 23.32 |
| Exacerbations (2021–2022) | 11 | 6 | 17 |
| Days on parenteral antibiotic treatment (mean ± SD) | 11.27 ± 5.84 | 11.33 ± 6.74 | 11.29 ± 5.96 |
Abbreviations - BMI: body mass index; ETI: Elexacaftor-Tezacaftor-Ivacaftor; FEV1: forced expiratory volume in the first second; SD: standard deviation.