Table 1.
Key Input Parameters for Developing a Microsimulation Model of Lung Cancer Screening in Patients With Comorbidities
| Model Parameter | Definition | Value | Sources | |
|---|---|---|---|---|
| Complications from Lung Cancer Screening | Probability of complications from lung cancer screening | Supplementary Table 1 | Previous work using PLCO26 | |
| Mortality from Non-Lung Cancer Causes | Death rates for non-lung cancer causes by age and comorbidity | Supplementary Table 2 | Secondary data, NHIS | |
| Comorbidity | Utility | |||
|---|---|---|---|---|
| Quality of Life for Patients With Comorbidities | Expected quality of life by comorbidity | Stroke | −0.051 | 27, 28, 29, 30, 31 |
| DM | −0.044 | |||
| COPD | −0.038 | |||
| CVD | −0.0235 |
COPD, chronic obstructive pulmonary disease; CVD, cardiovascular disease; DM, diabetes mellitus; NHIS, National Health Interview Survey; PLCO, Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial.