Table 4. Biomarkers of thymic epithelial tumors.
Methods | Thymoma | Thymic carcinoma | Thymic epithelial tumor |
---|---|---|---|
Genetic mutation | ZNF721, PABPC1, GTF2I | EGFR, ZNF429, BAP1, ABI1, BCL9L, CHEK2 | – |
Gene expression | – | – | CLDN4, FGF7, FGF10 |
Immunohistochemistry | – | CD70, CD8+, CD20+, CD204+, TIIC | SOX9, MAGE-A, NY-ESO-1, MAGE-C1, SAGE, GAGE7 |
qRT-PCR analysis | – | – | XLOC_003810 |
Serum concentration | – | – | HSP90α |
EGFR, epidermal growth factor receptor; qRT-PCR, quantitative real-time polymerase chain reaction; HSP90α, heat shock protein 90α.