Table S1. Characteristics of enrolled patients.
| Variables | No. of patients |
| NA, not available; EGJ, gastroesophageal junction; HER2, human epidermal growth factor receptor 2; PD-L1, programmed death-ligand 1; CPS, combined positive score; EBV, Epstein-Barr virus; pMMR, mismatch repair-proficient; dMMR, mismatch repair-deficient; TMB, tumor mutational burden; muts, mutations. | |
| Total | 536 |
| Age (year) | |
| <60 | 364 |
| ≥60 | 170 |
| NA | 2 |
| Sex | |
| Male | 336 |
| Female | 198 |
| NA | 2 |
| Histopathology | |
| Non-EGJ | 411 |
| EGJ | 113 |
| NA | 12 |
| Lauren | |
| Intestinal | 148 |
| Diffuse | 189 |
| Mixed | 100 |
| NA | 99 |
| Differentiation | |
| High | 5 |
| Moderate | 97 |
| Poor | 397 |
| NA | 37 |
| Metastasis site | |
| Liver | 144 |
| Lung | 51 |
| Peritoneum | 321 |
| Uterine adnexa | 90 |
| Lymph node | 28 |
| NA | 36 |
| HER2 status | |
| Positive | 53 |
| Negative | 448 |
| NA | 35 |
| PD-L1 status | |
| CPS≥1 | 203 |
| CPS<1 | 285 |
| NA | 48 |
| EBV status | |
| Negative | 403 |
| Positive | 6 |
| NA | 127 |
| MMR status | |
| pMMR | 461 |
| dMMR | 7 |
| NA | 68 |
| TMB (muts/Mb) | |
| TMB<10 | 96 |
| TMB≥10 | 23 |
| NA | 417 |