Overview of flowchart in study inclusion process and pie charts of basic subgroups of NEC. (A) Flowchart of whole study; (B) Primary tumor sites; (C) Detailed primary tumor sites; (D) Pathology subgroups. NEN, neuroendocrine neoplasm; NET, neuroendocrine tumor; NEC, neuroendocrine carcinoma; GEP, gastroenteropancreatic; LNEC, lung NEC; LCNEC, large-cell NEC; SCNEC, small-cell NEC; ENEC, esophagus NEC; GNEC, gastric NEC; DNEC, duodenum NEC; CRNEC, colorectal NEC; PNEC, pancreas NEC; BTNEC, bile tract NEC; UPNEC, unknown primary NEC.