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Drivers genes and TMB distributions for GEPNEC of different primary sites. (A) Sankey plots of distinct driver genes of high frequency in GPENEC with different locations; (B) Box plots of TMB of various primary sites of GEPNEC. TMB, tumor mutation burden; GEPNEC, gastroenteropancreatic neuroendocrine carcinoma; LNEC, lung NEC; GNEC, gastric NEC; UPNEC, unknown primary NEC; ENEC, esophagus NEC; DNEC, duodenum NEC; CRNEC, colorectal NEC; BTNEC, bile tract NEC; PNEC, pancreas NEC.
