Table S2. Parameters related to cardiac function.

Variables	NT-proBNP (pg/mL)			TNT-HS (pg/mL)			cTnI (μg/L)
		n (%)			n (%)			n (%)
The abnormal rate for NT-proBNP means the value higher than 125 pg/mL, for TNT-HS means the value higher than 14 pg/mL, for cTnI means the value higher than 0.04 μg/L. *, indicated P<0.05 (statistically significant). NT-proBNP, N-terminal pro-brain natriuretic peptide; TNT-HS, high-sensitivity troponin; cTnI, troponin I.
Baseline	40.6±29.6	0 (0)		4.0±2.8	0 (0)		0.002±0.004	0 (0)
Cycle 4	38.1±50.2	1 (1.3)		3.7±1.6	0 (0)		0.003±0.003*	0 (0)
Cycle 8	32.1±37.1*	1 (1.3)		3.4±0.8	0 (0)		0.005±0.004*	0 (0)