Table 1. Clinicopathologic features of 220 patients with distant metastatic differentiated thyroid cancer.
| Clinicopathologic features | n (%) | P | |
| Non-RAIR (N=81) | RAIR-DTC (N=139) | ||
| IQR, interquartile range; PTC, papillary thyroid cancer; FTC, follicular thyroid cancer; PDTC, poorly differentiated thyroid cancer; T, tumor; N, lymph node; RAIR, radioactive iodine-refractory; RAIR-DTC, radioactive iodine-refractory differentiated thyroid cancer; *, Part of data are not available; a, Brain, liver, pancreas, pleura, muscle, or distant metastatic lymph nodes, with or without lung and bone metastases. | |||
| Age at diagnosis (year) [median (IQR)] | 34.15 (28.80, 41.72) | 46.72 (35.27, 56.13) | <0.001 |
| Gender: female | 51 (63.0) | 78 (56.1) | 0.320 |
| Pathology | 0.441 | ||
| PTC | 74 (91.4) | 118 (84.9) | |
| FTC | 5 (6.2) | 12 (8.6) | |
| PTC and FTC | 1 (1.2) | 2 (1.4) | |
| PDTC | 1 (1.2) | 7 (5.0) | |
| T stage* | 0.064 | ||
| 1−3a | 47 (63.5) | 58 (46.8) | |
| 3b−4b | 27 (36.5) | 66 (53.2) | |
| N stage* | 0.145 | ||
| 0 | 11 (14.1) | 11 (8.9) | |
| 1a | 5 (6.4) | 10 (8.1) | |
| 1b | 62 (79.5) | 102 (82.9) | |
| Distant metastatic organs | 0.004 | ||
| Lung | 69 (85.2) | 96 (69.1) | |
| Bone | 3 (3.7) | 5 (3.6) | |
| Lung and bone | 8 (9.9) | 14 (10.1) | |
| Othersa | 1 (1.2) | 24 (17.3) | |
| Mutational load [median (IQR)] | 1 (1, 2) | 2 (1, 2) | <0.001 |