Table 4.
Univariable and multivariable logistic regression analysis of factors associated with BRAF mutation in sessile serrated lesions
| Factors | SSLs without BRAF mutation (n = 80), n (%) | SSLs with BRAF mutation (n = 41), n (%) |
Univariate analysis
|
Multivariate analysis
|
||
|
OR (95%CI)
|
P value
|
OR (95%CI)
|
P value
|
|||
| Age < 60 | 15 (34.9) | 42 (53.8) | 2.178 (1.009-4.699) | 0.045 | 2.118 (0.935-4.797) | 0.072 |
| Proximal localization | 51 (65.4) | 34 (79.1) | 2 (0.383-4.775) | 0.115 | 1.967 (0.777-4.979) | 0.153 |
| Size ≥ 10 mm | 40 (51.3) | 15 (34.9) | 0.509 (0.236-1.097) | 0.083 | 0.875 (0.368-2.082) | 0.762 |
| Flat morphology | 12 (15.4) | 13 (30.2) | 2.383 (0.973-5.836) | 0.054 | 1.766 (0.646-4.826) | 0.268 |
| No dysplasia | 53 (67.9) | 19 (44.2) | 2.627 (1.219-5.663) | 0.013 | 2.020 (0.880-4.633) | 0.097 |
SSLs: Sessile serrated lesions; OR: Odds ratio; CI: Confidence interval.