TABLE 3.

The results of statistical comparison of t‐tau levels between analyzed groups

Tested groups	The result of the statistical test
SMA 1, SMA 2, and SMA 3
BT vs. 4th dose	U = 4; Z = −2.16; p = 0.03
BT vs. 5th dose	U = 0; Z = −2.65; p = 0.01
BT vs. 6th dose	U = 0; Z = −2.95; p < 0.01
BT vs. 7th dose	U = 0; Z = −2.78; p < 0.01
BT vs. 9th dose	U = 0; Z = −2.72; p < 0.01
BT vs. 10th dose	U = 0; Z = −2.65; p = 0.01
BT vs. 11th dose	U = 0; Z = −2.45; p = 0.02
3rd dose vs. 7th dose	U = 5; Z = −2.01; p = 0.05
3rd dose vs. 9th dose	U = 4; Z = −2.04; p = 0.04
BT vs. 1st–5th dose	U = 11.50; Z = −2.36; p = 0.01
BT vs. 6th–10th dose	U = 7; Z = −3.04; p < 0.01
BT vs. 11th–15th dose	U = 3; Z = −2.04; p = 0.01
BT vs. 0–6 months	U = 11.5; Z = −2.729; p = 0.003
BT vs. 6–12 months	U = 7; Z = −2.471; p = 0.01
BT vs. 12–18 months	U = 0; Z = −3.004; p = 0.001
BT vs. 18–24 months	U = 0; Z = −2.449; p = 0.016
SMA 1
BT vs. 4th–6th dose	U = 2; Z = −2.04; p = 0.03
BT vs. 7th–9th dose	U = 1; Z = −1.94; p = 0.05
BT vs. 6th–10th dose	U = 1; Z = −2.16; p = 0.02
BT vs. 12–18 months	U = 0; Z = −2.012; p = 0.044

Abbreviations: BT, before therapy; SMA, spinal muscular atrophy.