Table 4.

Mediation effects of cognitive functions by domains

	RC1 (Prefrontal)			RC2 (Temporal-insula)			RC5 (Somatosensory / visual)
	B(SE)	Z	p-value	B(SE)	Z	p-value	B(SE)	Z	p-value
Mediators
Language	0.003(0.004)	0.733	0.464	0.015(0.014)	1.042	0.298	0.002(0.003)	0.738	0.460
Memory	-0.003(0.003)	-1.050	0.294	-0.019(0.013)	-1.477	0.14	0.002(0.003)	0.592	0.554
Visuospatial	0.000(0.003)	0.128	0.898	0.001(0.008)	0.170	0.865	0.000(0.001)	0.064	0.949
Executive/Speed	-0.017(0.006)	-2.694	0.007	-0.024(0.008)	-2.909	0.004	-0.004(0.004)	-0.965	0.334
MMSE-KC	-0.009(0.005)	-1.703	0.089	-0.027(0.014)	-1.952	0.051	0.003(0.004)	0.682	0.496
Indirect effect (X-M-Y)	-0.026(0.008)	-3.339	0.001	-0.054(0.014)	-3.805	< 0.001	0.003(0.008)	0.413	0.680
Total Effect (X-Y)	-0.066(0.026)	-2.514	0.012	-0.084(0.027)	-3.098	0.002	-0.078(0.029)	-2.666	0.008