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. 2023 Sep 26;30(3):e14456. doi: 10.1111/cns.14456

FIGURE 3.

FIGURE 3

NPGE treatment alleviated neuronal ferroptosis after I/R injury. (A–D) Representative immunofluorescence images of NeuN–positive cells and GPX4–positive cells in the penumbra region after CIRI, n = 5, scale bar 50 μm. (E, F) Western blot analysis of GPX4 in the ischemic penumbra tissue after CIRI, n = 6. (G, J) Western blot analysis of GPX4 in HT22 cells after OGD/R, n = 3. (H, I) The levels of Fe2+ and GSH in the brain after CIRI, n = 5. (K, L) The levels of Fe2+ and GSH in HT22 cells after OGD/R, n = 9. *p < 0.05, **p < 0.01, ***p < 0.001.