FIG. 5.

Adenovirus-delivered HCV-responsive CD expression. (A) Huh-NNRZ and Huh-7 cells were infected with AdmCMVcCDmpA (MOI, 0 to 200). After 48 h, cells were harvested and CD enzymatic activity was determined by measuring the conversion of 5-FC to 5-FU. (B) Huh-NNRZ and Huh-7 cells were mock infected or infected with AdmCMVcCDmpA at an MOI of 80 and maintained in the absence or presence of 5-FC. Viable cells were quantified after 4 days. Representative data are from three separate experiments. *, P < 0.05 compared with the control.