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. 2024 Mar 5;65(3):3. doi: 10.1167/iovs.65.3.3

Figure 4.

Figure 4.

A combined linear model based on quantitative metrics of foveal structure predicts BCVA in albinism more accurately than categorical foveal hypoplasia grade. The correlation between predicted BCVA (BCVApred) and observed BCVA (BCVAobs) was moderate for the predictive model based on categorical foveal hypoplasia grade (A, R = 0.622), but was stronger for the combined linear model based on quantitative structural metrics (B, R = 0.736). In panels A and B, dashed lines show where BCVApred = BCVAobs (i.e., perfect agreement between predicted and observed BCVA). When we plotted the difference between predicted and observed BCVA (BCVApred – BCVAobs) against the average of predicted and observed BCVA (BCVAmean), there was a negative trend in the bias for both the categorical predictive model (C) and the combined linear model (D); however, this trend was reduced in the combined linear model. In panels C and D, solid lines show bias, dashed lines show limits of agreement, and shaded gray areas show the 95% confidence intervals of the bias and limits of agreement.