TABLE 1.
Demographic and clinical information for study participants
| Females (n = 987) | Males (n = 1132) | |
|---|---|---|
| Age | 72.3 ± 7.2 | 74.2 ± 7.1 a |
| Education | 15.6 ± 2.7 | 16.4 ± 2.8 a |
| APOE ϵ4+ | 440 (45%) | 512 (45%) |
| Baseline diagnosis | ||
| NC | 424 (54%) | 346 (42%) a |
| MCI | 398 (31%) | 579 (40%) a |
| AD | 165 (15%) | 207 (18%) |
| BMI | 26.6 ± 5.5 | 27.2 ± 4.1 |
| Systolic BP | 134.3 ± 17.7 | 134.7 ± 17.2 |
| Diastolic BP | 73.9 ± 10.2 | 75.1 ± 9.6 |
| Hypertension | 435 (44%) | 574 (51%) a |
| Diabetes | 54 (5%) | 111 (10%) a |
| Stroke | 8 (1%) | 19 (2%) |
| Smoking | 276 (28%) | 436 (39%) a |
| Alcohol abuse | 21 (2%) | 61 (6%) a |
| Hachinski score | ||
| 0 | 509 (51.5%) | 517 (46%) |
| 1 | 419 (42.5%) | 540 (48%) |
| 2 | 33 (3.3%) | 44 (4%) |
| 3 | 24 (2%) | 25 (2%) |
| 4 | 2 (< 1%) | 6 (< 1%) |
Notes: Values are represented as mean ± standard deviation or as the amount of the sample and percentage of sample with that trait.
Abbreviations: AD, Alzheimer's disease; APOE, apolipoprotein E; BMI, body mass index; BP, blood pressure; MCI, mild cognitive impairment; NC, normal controls.
a
Males had statistically (p < 0.05) increased age, higher education, more MCI participants and fewer NCs, and higher rates of hypertension, diabetes, smoking, and alcohol abuse.