TABLE 1.
Sample characteristics.
| Carriers (n = 27) | Non‐carriers (n = 26) | P‐value | |
|---|---|---|---|
| Age (years) | 35.93 ± 8.18 (24–53) | 37.04 ± 6.48 (24–48) | 0.586 |
| Sex (female/male) | 19F / 8M | 23F / 3M | 0.105 |
| Education (years) | 10.19 ± 3.26 (4–17) | 10.58 ± 4.67 (3–20) | 0.724 |
| GDS‐15 | 2.11 ± 2.61 (0–11) | 2.85 ± 3.54 (0–13) | 0.681 |
| Mini‐Mental State Examination | 28.74 ± 1.87 (24–30) | 29.69 ± 0.55 (28–30) | 0.085 |
| CERAD delayed recall | 5.70 ± 2.49 (1–9) | 7.38 ± 1.79 (4–10) | 0.007 |
| Subjective memory complaints | 14.56 ± 9.70 (1–35) | 9.12 ± 6.11 (3–24) | 0.018 |
| Intracranial volume (mm3) |
1.41 × 106 ± 1.08 × 105 (1.20 × 106 − 1.64 × 106) |
1.35 × 106 ± 1.28 × 105 (1.05 × 106 − 1.57 × 106) |
0.091 |
| Hippocampal volume (mm3) | 3866.85 ± 568.80 (2622–4883) | 4089.94 ± 370.92 (3402–4734) | 0.097 |
Note. Group differences in age, education, CERAD delayed recall, subjective memory complaints, hippocampal volume, and intracranial volume were conducted using an independent sample t test. Group differences in GDS‐15 and Mini Mental State Examination scores were conducted using Mann–Whitney U tests. Group differences in sex were conducted using chi‐square tests. Means ± standard deviation given for continuous measures with observed range in parentheses.
Abbreviations: CERAD: Consortium to Establish a Registry for Alzheimer's Disease; GDS‐15: Geriatric Depression Scale (15‐item).