TABLE 2.
Sex‐by‐time ANOVAs for hippocampal functional connectivity during the face–name associative memory fMRI task controlling for age.
| Brain Region | Brodmann area (BA) | Peak MNI coordinates (x,y,z) | Size (mm3) | β Value of ROI Time 1 Mean (SD) | β Value of ROI Time 2 Mean (SD) | Sex* Time F‐value |
Sex* Time p‐value |
|---|---|---|---|---|---|---|---|
| Left hippocampal functional connectivity | |||||||
| ACC | BA 24 | −2, 33, 10 | 1128 | Male: −0.22 (1.54) Female: 0.32 (0.92) | Male: 0.50 (1.28) Female: −0.61 (1.30) | F = 10.80 | p = 0.0014** |
| MFG | BA 10, 32 | –4, 56, 14 | 3504 | Male: −0.089 (2.24) Female: 0.93 (1.27) | Male: 0.85 (1.77) Female: −0.38 (1.64) | F = 12.89 | p = 0.00052*** |
| Hippocampus | N/A | 32, −30, −8 | 1408 | Male: 0.47 (0.91) Female: −0.48 (1.22) | Male: −0.20 (0.67) Female: 0.34 (0.98) | F = 12.06 | p = 0.00077*** |
| Right hippocampal functional connectivity | |||||||
| MFG | BA 10, 32 | −6,52,10 | 1608 | Male: −0.50 (1.95) Female: 0.17 (1.17) | Male: 0.61 (1.86) Female: −0.55 (1.25) | F = 12.43 | p = 0.00064*** |
Abbreviations: ACC, anterior cingulate cortex; ANOVA, analysis of variance; BA, Brodmann area; L, left; MFG, middle frontal gyrus; MNI, Montreal Neurologic Institute; R, right.
*p < 0.05; **p < 0.01, ***p < 0.001.