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. 2005 May;79(10):6005–6022. doi: 10.1128/JVI.79.10.6005-6022.2005

FIG. 6.

FIG. 6.

Glioblastoma-adapted VSV-rp30: enhanced targeting of diverse glioma phenotypes. The glioblastoma-adapted strain VSV-rp30 was compared to the original VSV-G/GFP. (A) VSV-rp30 presents a strong tropism for numerous tested glioblastoma cell lines. Representative photomicrographs are shown here for U-87 MG, M059J, U-118 MG, A-172, and U-373 MG cells. The MOI for VSV and VSV-rp30 was 10. (B) Bar graph comparing the infection rates of VSV and VSV-rp30 on U-373, A-172, U-118, M059J, and U-87 at 10 MOI. Values represent mean of 10 microscopic fields. In each cell line, pairs of micrographs showing VSV or VSV-rp30 and analysis of cell infection were made at the same time postinoculation (<12 h).