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The PET tracer [11C]‐Butanol was used as a biomarker for CSF clearance. The data show in elderly individuals with brain amyloid deposits ([11C]‐PiB imaging) that compared with controls, nasal turbinate tracer drainage is slower. These data suggest that the slowed ventricular CSF drainage found in neurodegenerative diseases such as Alzheimer's can be detected peripherally
