FIG. 1.

Nucleotide sequence comparison of human and murine gene 5′-flanking regions. The Kanehisa program was used to compare the human (upper) and murine (lower) 5′-flanking sequences of the CIS gene. The murine sequence corresponds to the sequence published by Matsumoto et al. (20). These sequences are numbered such that +1 refers to the translation initiation codon of the CIS protein. Positions of transcription start sites are indicated by arrows. The consensus binding sites for STAT and SP1 are boxed.