FIG. 2.

Blockade of wt and srr7 infection in mixed neural cell cultures by anti-MHVR MAb CC1. Mixed neural cell cultures were treated with 10-fold-stepwise-diluted CC1 at 37°C for 1 h and then infected with either wt virus or srr7. After infection, cells were cultured in the presence of CC1. Viral antigen was visualized by staining with anti-MHV MAbs at 12 and 24 h after wt and srr7 infection, respectively, and antigen-positive cells were counted. The blockade of viral infection by CC1 was calculated as the percentage of viral antigen-positive cells in the presence of CC1 compared with cell numbers obtained in the absence of CC1.