TABLE 4.
Numbers of genes with significant change of expression in different categories and subcategories
| Category and subcategory | No. of genes
|
|||
|---|---|---|---|---|
| Total | SARS- CoV | HCoV- 229E | Both SARS-CoV and HCoV-229E | |
| Apoptosis | 23 | |||
| Antiapoptosis | 3 | 3 | 0 | 0 |
| Proapoptosis | 12 | 7 | 2 | 3 |
| DNA repair | 5 | 2 | 2 | 1 |
| Other | 3 | 2 | 1 | 0 |
| Inflammation | 34 | |||
| Antiinflammatory | 2 | 2 | 0 | 0 |
| Proinflammatory | 24 | 21 | 0 | 3 |
| Immunomodulatory | 2 | 1 | 1 | 0 |
| Other | 6 | 5 | 1 | 0 |
| Coagulation | 5 | |||
| Anticoagulants | 1 | 0 | 0 | 1 |
| Procoagulants | 4 | 4 | 0 | 0 |
| Metabolism | 35 | |||
| Amino acid | 4 | 2 | 1 | 1 |
| Carbohydrate | 7 | 6 | 0 | 1 |
| Lipid | 5 | 5 | 0 | 0 |
| Transporter | 10 | 6 | 1 | 3 |
| Other | 9 | 7 | 2 | 0 |
| Signal Transduction | 18 | 15 | 1 | 2 |
| Transcription | 37 | 25 | 3 | 9 |
| Cell Cycle | 17 | 12 | 3 | 2 |
| Cell growth and differentiation | 7 | 6 | 0 | 1 |
| Stress response | 7 | 6 | 0 | 1 |
| Miscellaneous | 16 | 11 | 1 | 4 |
| Unknown | 25 | 16 | 2 | 7 |
| Total | 224 | 164 | 21 | 39 |