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. 2024 Feb 14;11:1288854. doi: 10.3389/fmed.2024.1288854

Table 3.

List of experimentally validated miRNA:gene pairs between 770 glaucoma-associated genes received from the DisGeNET 7.0 database and two miRNAs (hsa-miR-193a-5p and hsa-miR-222-3p) using multiMiR 1.10.0 package.

Target gene name
hsa-miR-193a-5p hsa-miR-222-3p
MTOR CDKN1B
WT1 ETS1
MMP1
PTEN
SOD2
TIMP3

The pairs here only include those validated with strong evidence, including luciferase reporter assay, western blot, and RT-PCR. The whole list is listed in the Supplementary Table S3. MTOR; mammalian target of rapamycin, WT1; Wilms tumor protein, CDKN1B; cyclin dependent kinase inhibitor 1B, ETS1; ETS proto-oncogene 1 (transcription factor), MMP-1; matrix metalloproteinase-1, PTEN; phosphatase and tensin homolog, SOD2; superoxide dismutase 2, TIMP3; TIMP.