Table 3.
List of experimentally validated miRNA:gene pairs between 770 glaucoma-associated genes received from the DisGeNET 7.0 database and two miRNAs (hsa-miR-193a-5p and hsa-miR-222-3p) using multiMiR 1.10.0 package.
| Target gene name | |
|---|---|
| hsa-miR-193a-5p | hsa-miR-222-3p |
| MTOR | CDKN1B |
| WT1 | ETS1 |
| MMP1 | |
| PTEN | |
| SOD2 | |
| TIMP3 | |
The pairs here only include those validated with strong evidence, including luciferase reporter assay, western blot, and RT-PCR. The whole list is listed in the Supplementary Table S3. MTOR; mammalian target of rapamycin, WT1; Wilms tumor protein, CDKN1B; cyclin dependent kinase inhibitor 1B, ETS1; ETS proto-oncogene 1 (transcription factor), MMP-1; matrix metalloproteinase-1, PTEN; phosphatase and tensin homolog, SOD2; superoxide dismutase 2, TIMP3; TIMP.