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. 2005 May;79(10):6511–6515. doi: 10.1128/JVI.79.10.6511-6515.2005

TABLE 1.

Reactivity of E protein-specific MAbs with full-length and truncated E trimers in a blocking ELISAa

MAb Full-length E trimer sE trimer
Domain I
    C1 +++ ++/+++
    C2 +/++ +
    C3 + −/+
    C4 + +
    C5 ++ ++
    C6 + +
    i2 − −b
    IC3 + +
Domain II
    A1 − +++
    A2 − +++
    A3 + +++
    A4 − −b
    A5 +++ +++
Domain III
    B1 −/+ +
    B2 ++ ++
    B3 +++ +++
    B4 ++ ++/+++
a

+++, 75-100% blocking; ++, 50-75% blocking; +, 25-50% blocking; −, 0-25% blocking

b

These MAbs lose their reactivity upon dimer-trimer conversion.