Fig. 1.

Outcome for patients who underwent LT in LEN-TAP trial

a Radiological and pathological response for three patients who underwent LT. Target lesion and tumour thrombus (indicated by red arrows) necrosis and ascites were found after treatment; tumour-free images were obtained one year after LT; no residual tumour cells were found in explanted liver. b AFP trends between initiation of LEN-TAP therapy and pre-transplant. AFP decreased dramatically in these three patients after downstaging therapy. c Programmed cell death protein 1 inhibitor cycles before transplant, pathological response and survival time for patients received LT. LT, liver transplantation; LEN-TAP, lenvatinib, transarterial chemoembolization and PD-1 inhibitor therapy; AFP, alpha-fetoprotein; RFS, recurrence-free survival; OS, overall survival; pCR, pathological complete response.