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. 2024 Apr 1;15(2):640–697. doi: 10.14336/AD.2023.0520

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Copyright: © 2024 Chan et al.

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Figure 6. — The roles of herbal medicine act in modulating MYC-driven malignant cells. ABC Transporter: ATP-binding cassette transporters; Acetyl-CoA: acetyl coenzyme A; AP-1: Activator protein 1; CD 47: Cluster of Differentiation 47; CD57: Cluster of Differentiation 57; ER: Endoplasmic Reticulum; G0: gap phase; G1 phase: gap 1 phase; G2: Growth 2 phase; GPX4: Glutathione peroxidase 4; GSH: glutathione; H19: H19 Imprinted Maternally Expressed Transcript; IL-1β: Interleukin-1 Beta; IL-18: Interleukin-18; IL-6: Interleukin-6; JAK: Janus kinase; M: Mitosis phase; MDM2: murine double minute 2; NF-κB: Nuclear factor kappa B; Notch: Neurogenic locus notch homolog protein; Nrf2: nuclear factor erythroid 2-related factor 2; PD-1: Programmed cell death protein 1; PD-L1: Programmed death ligand-1; S: Synthesis Phase; STAT3: Signal Transducer And Activator Of Transcription 3; TGF-β1: Transforming growth factor beta-1.