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. 2024 Jan 18;27(3):547–560. doi: 10.1038/s41593-023-01554-7

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a,b, FLIP steps for an example probe. First, FLIP automatically computes the relative power map (a) and the mean relative power across the alpha-beta (10–19 Hz, blue) and gamma (75–150 Hz, red) optimal bands. Then, it identifies the channel range d where the G value of the alpha-beta and gamma relative power regressions (dashed black lines) is maximal (b). Finally, it identifies the alpha-beta peak (blue arrow), gamma peak (red arrow) and crossover (green arrow) channels as markers for layers 5/6, 2/3 and 4, respectively. c, Histogram showing distribution of G across all probes. Dashed lines, ±G threshold. d, Mean relative power map across all probes with non-significant alpha-beta and gamma relative power regressions. e, Mean relative power map across probes within each of the four colored ranges of G shown in c.