Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jan 24;27(3):433–448. doi: 10.1038/s41593-023-01558-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Extended Data Fig. 7 — a, Representative CAP traces of ctrl and cKO at baseline and post 50 Hz stimulus train, highlighting changes in CAP peak amplitude and latency (blue arrows). b-d, Analysis of CAP peak latency changes to 1 min 50 Hz in ctrl (n = 8 mice) and cKO (n = 16 mice): b, Average % changes (± SEM) from baseline in CAP peak latency showing slower recovery in cKO. c, CAP peak latency analysis at the end the stimulation revealing larger increase in latency in cKO compared to ctrl (p = 0.0232, two-sided Student’s t-test). d, Analysis of CAP peak latency recovery time post stimulation, significantly slower in cKO compared to ctrl (p < 0.0001, two-sided Student’s t-test). e-j, 25 Hz-induced CAP changes in ctrl (n = 4 mice) and cKO (n = 7 mice). e-g: CAP peak amplitude: e, Average % changes in peak amplitude. f, Greater decrease in cKO (p = 0.0203, two-sided Student’s t-test). g, Slower recovery post-stimulation in cKO (p = 0.0059, two-sided Student’s t-test). h-j, CAP peak latency: h, Average % changes in latency. i, Larger increase in cKO mice (p = 0.0093, two-sided Student’s t-test). j, Slower recovery post-stimulation in cKO (p = 0.0007, two-sided Student’s t-test). k-p, 10 Hz-induced CAP changes in ctrl (n = 4 mice) and cKO (n = 8 mice). k-m, CAP peak amplitude: k, Average % changes in peak amplitude. l, Greater decrease in cKO mice (p = 0.0242, two-sided Student’s t-test). m, Slower recovery post-stimulation in cKO (p = 0.0083, two-sided Student’s t-test). n-p, CAP peak latency: n, Average % changes in latency. o, Larger increase in cKO mice (p < 0.0001, two-sided Student’s t-test). p, Slower recovery post-stimulation in cKO (p = 0.0324, two-sided Student’s t-test). Data are represented as dot-plots with means ± SEM.