Table 2.

Treatment-related AEs

	Grade 1/2	Grade 3/4
Leukopenia	12 (55%)	2 (9%)
Neutropenia	7 (32%)	7 (32%)
Anemia	14 (64%)	1 (5%)
Thrombocytopenia	2 (9%)	1 (5%)
Hypofibrinogenemia	12 (55%)	4 (18%)
Prolonged activated partial thromboplastin time	10 (45%)	0
Hypoalbuminemia	15 (68%)	1 (5%)
Hyperbilirubinemia	16 (73%)	0
ALT elevation	9 (41%)	1 (5%)
AST elevation	11 (50%)	1 (5%)
Creatine	3 (14%)	0
Hyponatremia	11 (50%)	0
Hyperkalemia	7 (32%)	0
Serum amylase increased	3 (14%)	0
Hyperglycemia	3 (14%)	0
Hypertriglyceridemia	4 (18%)	1 (5%)
Hypothyroidism	8 (36%)	0
Nausea	5 (23%)	0
Vomiting	1 (5%)	0
Diarrhea	0	0
Mucositis	5 (23%)	0
Infection	0	0
Heart failure	0	1 (5%)