Table 2.
GO category | Downregulated gene | Gene description | Fc Podo vs HC | P value |
---|---|---|---|---|
Histones | H3C12 | H3 clustered histone 12 | 3.1 | 0.0002 |
H2AC12 | H2A clustered histone 12 | 3 | 0.0002 | |
H2BC14 | H2B clustered histone 14 | 2.8 | 0.001 | |
H3C8 | H3 clustered histone 8 | 3.1 | 0.0002 | |
Cell division cycle | CDC6 | Cell division cycle 6 | 2.3 | 0.0001 |
CDCA5 | Cell division associated 5 | 2.6 | 0.003 | |
Immunoglobulin domain | IGLV3–21 | Immunoglobulin lambda variable 3–21 | 4.9 | 0.005 |
IGLV1–47 | Immunoglobulin lambda variable 1–47 | 3.5 | 0.007 | |
IGLC3 | Immunoglobulin lambda constant 3 | 3 | 0.006 | |
IGLC2 | Immunoglobulin lambda constant 2 | 2 | 0.03 | |
T-cell receptor | TRAV26-1 | T-cell receptor alpha variable 26-1 | 1.57 | 0.03 |
TRAV10 | T-cell receptor alpha variable 10 | 1.74 | 0.04 | |
TRBC1 | T-cell receptor beta constant 1 | 1.75 | 0.03 |
GO gene ontology, Fc fold change, HC healthy controls, vs versus.
Gene names are italicized.