Fig. 1.
Metabolomics of septic shock in comparison to ambulatory controls, bacteremia without sepsis and cardiogenic shock adjusted for age and sex. Volcano plots of septic shock (n = 42) in comparison to A ambulatory controls (n = 19), B bacteremia without sepsis (n = 18), and C cardiogenic shock (n = 19). Dashed lines denote Padj = 0.05. Venn diagrams quantifying the metabolites significantly (Padj < 0.05) D increased and E decreased in comparison to septic shock with an accompanying list of the metabolites significantly different in septic shock in comparison to all three comparator groups. “f-Met” = N-formyl-l-methionine; “Lac-Phe” = N-Lactoyl-phenylalanine