Fig. 2.

Relationship of f-Met and serine to sepsis severity and mortality. A Relative quantification of f-Met for all subjects. Solid line denotes median. Kruskal–Wallis multiple comparisons test of statistical significance. B Correlation of f-Met and Sequential Organ Failure Assessment (SOFA) score for septic shock subjects. Pearson correlation coefficient. C Relative quantification of f-Met in septic shock 28-day survivors (n = 28) vs. non-survivors (n = 14). Mann–Whitney test of statistical significance. D Absolute quantitation of serine for all subjects. Solid line denotes median. Kruskal–Wallis multiple comparisons test of statistical significance. E Correlation of serine and SOFA score for septic shock subjects. Pearson correlation coefficient. F Absolute quantitation of serine in septic shock 28-day survivors (n = 28) vs. non-survivors (n = 14). Mann–Whitney test of statistical significance. * = P < 0.05, ** = P < 0.01, *** = P < 0.001, **** = P < 0.0001