Fig. 3.

N-Lactoyl-amino acids vs. lactate as distinguishers of sepsis severity and mortality. Absolute quantitation of all subjects (A–E); septic shock subjects divided by SOFA score (n = 12, 15, 15) (F–J); and septic shock 28-day survivors (n = 28) vs. non-survivors (n = 14) (K–O) for the indicated metabolite. For comparisons of illness groups and septic shock SOFA groups, Kruskal–Wallis multiple comparisons test of statistical significance. For comparisons of septic shock mortality, Mann–Whitney test of statistical significance. * = P < 0.05, ** = P < 0.01, *** = P < 0.001, **** = P < 0.0001