Table 2.

Cytoarchitectonic characteristics of DLPFC areas SFG2, SFG3, SFG4, MFG4, MFG5 and neighboring areas.

Area		Cytoarchitectonic characteristics
SFG2	II III IV V VI	Cell dense and thick with a blurry border to layer III Subdividable with more loosely packed cells in layers IIIa and IIIb IIIc with medium-sized pyramidal cells Definable, but fewer cells compared to SFG4, MFG4, and MFG5 Medium to large-sized pyramidal cells, larger cells compared to IIIc, without subdivision Prominent and broad Blurry transition to white matter
SFG3	II III IV V VI	Thin with a clear border to layer III compared to SFG2 Pyramidal cell gradient along layer III with medium-sized pyramidal cells in deeper IIIc Poorly developed with blurry layers Sub-dividable with large pyramidal cells in Va and pale Vb with low cell density Cell dense with medium-sized pyramidal cells in VIa and thin pale VIb Sharp border to white matter
SFG4	II III IV V VI	Thin with a sharp border to layer III More loosely packed medium-sized cells in IIIa and IIIb compared to MFG4 and larger pyramidal neurons in IIIc Densely packed and well-definable Pyramidal neurons in Va are smaller compared to layer IIIc and pale layer Vb Cell dense Blurry white-matter border compared to SFG3
MFG4	II III IV V VI	Prominent but thin with a blurry border to layer III More cell dense compared to SFG4 with medium to large-sized neurons in deeper IIIc Well developed Medium to large-sized cells distributed across the layer Prominent, cell dense, and broad White-matter transition sharper as compared to SFG4
MFG5	II III IV V VI	Thin with a blurry transition to layer III High cell density with a gradient in cell size to IIIc Visible but thinner than in MFG4 Medium to large-sized pyramidal cells Thin and cell-dense Sharp border to white matter
Fp1		Sharp border between layers I, II, and III Dense layer II and deeper layer III Layer IV more pronounced than in SFG3 Pyramidal cells in layer V are not as large as in SFG2
SFS1		Homogenous appearance with uniformly packed layer III than SFG2 Dense, well-definable layer IV Medium-sized pyramidal cells in layer V and thin layer VI compared to SFG2 Sharp border between layer VI and white matter
SFS2		Sparser cell packing than in MFG4 Blurry, not well-definable layer IV Layer V and VI are less developed compared to MFG4
MFG1		Large pyramidal cells in deeper layer IIIc Broader layer IV than in SFS2 but not as dense as compared to MFG2 Prominent layer VI with large cells and blurry border to white matter
45		Large pyramidal cells in deep layer IIIc compared to MFG5 Layer IV visible but less developed than in MFG5 White matter transition bot as sharp as in MFG5
6d3		Agranular cortex with poor lamination across layers Pyramidal cell clusters in layer V
8d1		Cell-rich layer II compared to cell-poor superficial layer III with more prominent layer IIIc Layer IV as weak stripe, cell-rich superficial layer (Va), and stripe-like cell-poor layer Vb
8d2		Less densely packed granular layer II compared to 8d1 Thin, visible layer IV and large pyramidal cells in Va and a light band, poor in cells (Vb) High cell density in layer VI with a sharp contrast to white matter
8v1		Columnar arrangement of pyramidal cells in layers III to V with hardly prominent but Visible layer IV Very prominent layer VI with high volume and cell density
8v2		Narrow and densely packed layer II Highly distinctive stripe as layer IV and subdividable layer V Tightly packed cell layer in layer VI
ifs1		Subdivision of layer III with small densely packed neurons in deeper layer III Thin and narrow layer IV Indistinct border between layers V and VI
ifs3		Cells arranged in columns Indistinct layer IV Large pyramidal cells in deeper layer III