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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Mol Psychiatry. 2023 Sep 7;28(11):4766–4776. doi: 10.1038/s41380-023-02236-3

Fig 5. Adaptor protein complex 2 α1 and alcohol-related phenotypes across species.

Fig 5.

A Bioinformatics analysis linking AP2A1 to alcohol-related behaviors in mouse, monkey, and human. CeA, central nucleus of the amygdala; CTA, conditioned taste aversion; Diff. Exp., differential expression; GS, GeneWeaver.org gene set number; HICs, handling induced convulsions; QTL, quantitative trait locus. B Cortical expression of Ap2a1 correlated with alcohol drinking in 23 control and alcohol dependent BXD recombinant inbred strains. C The B allele at Ap2a1 increased alcohol drinking in 44 BXD strains (*p < 0.05; mean ± s.e.m.).