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. 2024 Feb 23;10(5):e26736. doi: 10.1016/j.heliyon.2024.e26736

Table 3.

Predictors associated with higher plasma and saliva carbamazepine level.

Variable B (standard error) p value 95% confidence interval for B
Predictors associated with increased plasma carbamazepine levels
Constant 4.704 (1.217) <0.001 2.272–7.135
Frequency of seizures, aggregated categorical variable 0.610 (0.263) 0.023 0.085–1.135
Predictors associated with increased plasma carbamazepine levels, fine variables details
Constant (reference, seizure free) 5.309 (1.150) <0.001 3.008–7.610
Seizure daily 2.702 (3.253) 0.409 −3.807–9.212
2- 3 seizures weekly 0.859 (1.992) 0.668 −3.127–4.845
Seizures weekly 0.022 (2.738) 0.994 −5.456–5.500
Seizures monthly 2.617 (1.657) 0.120 −0.699–5.934
Seizures less than monthly 3.121 (1.427) 0.033 0.267–5.976
Predictors associated with increased saliva carbamazepine levels
Constant 0.969 (0.371) 0.012 0.225–1.712
Frequency of seizures, aggregated categorical variable 0.184 (0.079) 0.023 0.027–0.341
Predictors associated with increased saliva carbamazepine levels, fine variables details
Constant (reference, seizure free) 1.071 (0.349) 0.003 0.371–1.772
Seizure daily 0.370 (0.891) 0.680 −1.416–2.156
2- 3 seizures weekly 1.032 (0.560) 0.071 −0.092–2.155
Seizures weekly −0.483 (0.891) 0.590 −2.269–1.303
Seizures monthly 0.498 (0.475) 0.299 −0.454–1.450
Seizures less than monthly 1.120 (0.419) 0.010 0.279–1.960