Figure 3.
TRM cell abundance is positively associated with melanoma prognosis
The PC1 score can represent the 11 TRM signatures and the TRM cell proportion in melanoma.
(A) The correlation of TRM signatures with immune infiltration in TCGA-SKCM.
(B) Forest plot showing almost all the 11 TRM signatures were significantly associated with good prognosis.
(C) Survival analysis for TRM signatures.
(D) The correlation of the TRM signatures with each other.
(E) Principal Component Analysis (PCA) on the expression of the 11 TRM signatures in TCGA-SKCM patients.
(F) The correlation of PC1 and the TRM cell abundance.
(G) Kaplan-Meier plot showing the association between overall survival and Principal Component 1 (PC1) in TCGA-SKCM.
(H) Forest plot depicting hazard ratios of univariate Cox regression models evaluating the association between overall survival and several clinical variables.