Figure 7.

The Gene Set Enrichment Analysis (GSEA) analysis

(A) Low-risk patients with significant up-regulated memory T cell and immune-related pathways in the melanoma.

(B) The relationship between the PC1 and risk score.

(C‒F) GSEA indicated the tendency of individual pathways to be up- or down-regulated in response to high PC1 compared to low PC1 patients or low risk compared to high-risk patients. T cell-mediated immunity pathway is up-regulated (C), memory T cell differentiation pathway is up-regulated (D), and skin epidermis development and melanocyte differentiation-related pathways are down-regulated (E and F, respectively).