Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
HBx involvement in promoting hepatocarcinogenesis. HBx protein operates on numerous receptors, transcription factors, and components of the transcription machinery, thus dysregulating various cellular signalling pathways and epigenetic components. rcDNA: relaxed circular DNA; CASP3: caspase-3; Egr2/3: early growth response gene 2/3; VDAC3: voltage-dependent anion chanel 3; CycE: cyclin E; STAT3/5: signal transducer and activator of transcription 3/5; GSH: glutathione; FasL: Fas ligand
