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Exemplary images taken from H&E stained lymph node from esophageal cancer patients. The figure illustrates the visually perceivable differences between immunologically stimulated (also called reactive) LNs. Figure A shows a lymph node with a large number of germinal centers (some are highlighted in asterisk), indicative of follicular hyperplasia; Figure B contains a metastatic lymph node with hyperplasia of paracortex and a lack of germinal centers.
