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. 2024 Mar 6;7(3):e241349. doi: 10.1001/jamanetworkopen.2024.1349

Table 2. Results From the Multilevel Negative Binomial Regressiona.

Variable and model Median log rate % in ROPE IRR (95% HDI) Posterior probability of IRR >specified threshold, %
1.0 1.1 1.2 1.3 1.4
Overall
Methylphenidate: baseline vs follow-up 0.34 0 1.41 (1.09-1.88) 99 96 87 72 52
Controls, baseline vs follow-up 0.17 13.76 1.18 (1.02-1.37) 98 82 40 10 1
Methylphenidate vs controls 0.18 28.65 1.19 (0.88-1.64) 87 70 49 30 16
No previous CVD
Methylphenidate: baseline vs follow-up 0.55 0 1.74 (1.24-2.42) 100 99 98 95 88
Controls: baseline vs follow-up 0.35 0 1.42 (1.15-1.72) 100 100 95 81 55
Methylphenidate vs controls 0.20 25.92 1.23 (0.84-1.87) 84 70 54 39 26
Previous CVD
Methylphenidate: baseline vs follow-up 0.01 39 1.00 (0.65-1.54) 48 31 19 10 5
Controls: baseline vs follow-up –0.10 50.17 0.90 (0.75-1.11) 17 3 0 0 0
Methylphenidate vs controls 0.09 33.77 1.09 (0.68-1.74) 65 49 35 24 15
Difference
Previous CVD vs no history 0.11 24.90 1.11 (0.58-2.13) 62 50 36 23 11

Abbreviations: CVD, cardiovascular disease; HDI, highest density interval; IRR, incidence rate ratio; ROPE, region of practical equivalence.

a

Baseline was used as the reference category.