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. Author manuscript; available in PMC: 2024 Mar 7.
Published in final edited form as: J Am Coll Cardiol. 2022 Oct 25;80(17):1633–1644. doi: 10.1016/j.jacc.2022.08.756

CENTRAL ILLUSTRATION. CD4 Subsets and Incident Cardiovascular Disease, Heart Failure, and Atherosclerotic Cardiovascular Disease.

CENTRAL ILLUSTRATION

CENTRAL ILLUSTRATION

CENTRAL ILLUSTRATION

Adjusted Cox proportional hazards model assessing the relationship of baseline T cell subsets and (A) composite cardiovascular disease (CVD) (including heart failure, acute myocardial infarction, unstable angina, coronary artery revascularization, and ischemic stroke), (B) incident heart failure, and (C) incident atherosclerotic CVD (including acute myocardial infarction, unstable angina, coronary artery revascularization, and ischemic stroke). Adjusted for age, race/ethnicity, cytomegalovirus antibody status, hypertension, diabetes, lipid levels, body mass index, hepatitis C virus status, hemoglobin, smoking status, estimated glomerular filtration rate, history of alcohol abuse, cocaine abuse, interleukin-6, D-dimer, and soluble CD14. HRs are reported per SD increment with 95% CIs, and no corrections for multiple testing were applied.