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. 2024 Feb 22;9(9):10030–10048. doi: 10.1021/acsomega.3c09780

Table 4. Drugs, Type of Study, and Their Molecular Mechanism.

compound type of study molecular mechanism references
sulforaphane in vitro inhibits histone deacetylases and DNA methyltransferase expression (199)
fucoxanthin in vivo induces GSH and GSS (183)
curcumin in vitro suppresses cyclin D and phosphorylated retinoblastoma (187)
epigallocatechin-3-gallate in vitro inhibits DNA methylation (192)
mangiferin - down-regulates NFkB (198)