Table 4. Drugs, Type of Study, and Their Molecular Mechanism.
compound | type of study | molecular mechanism | references |
---|---|---|---|
sulforaphane | in vitro | inhibits histone deacetylases and DNA methyltransferase expression | (199) |
fucoxanthin | in vivo | induces GSH and GSS | (183) |
curcumin | in vitro | suppresses cyclin D and phosphorylated retinoblastoma | (187) |
epigallocatechin-3-gallate | in vitro | inhibits DNA methylation | (192) |
mangiferin | - | down-regulates NFkB | (198) |