Table 2.
Lead SNPs across cohorts. List of the general CHD lead SNP across the cohorts used in this study. NA signifies not available (SNP not present in summary statistics). OR [95% CI] signifies Odds ratio [95% confidence interval]
| FinnGen | UKB | Meta-analysis | ||||
|---|---|---|---|---|---|---|
| SNP | OR [95% CI] | p | OR[95%CI] | p | OR[95%CI] | p |
| rs35046143 | 1.15[1.10–1.21] | 7.1 × 10–9 | NA | NA | NA | NA |
| rs2316327 | 1.17[1.12–1.23] | 1.5 × 10–9 | 1.08[1.00–1.17] | 6.0 × 10–2 | 1.14[1.09–1.20] | 2.0 × 10–9 |
| rs1293973611 | 4.48[2.80–7.17] | 7.0 × 10–10 | NA | NA | NA | NA |
| rs16941382 | 1.17[1.11–1.24] | 5.5 × 10–9 | 1.11[1.02–1.19] | 2.1 × 10–2 | 1.15[1.11–1.20] | 1.5 × 10–9 |