Table 2.
Percentages of the genotypic (n) and the mutant [1014F] allelic (95% confidence interval) frequencies of the kdr gene in Anopheles gambiae s.l. populations by period and species using a layered 2 × 3 × 3 contingency table
| Species | Period | Mos (n) | RR 1014F/1014F |
RS 1014L/1014F |
SS 1014L/1014L |
F† [1014F allele] |
P |
|---|---|---|---|---|---|---|---|
| Ag | BIRS | 80 | 40% (32)a | 58% (46)a | 3% (2)a | 69% (62–76%) | < 0.001 |
| DIRS | 90 | 77% (69)b | 22% (20)b | 1% (1)a | 88% (83–93%) | ||
| WIRS | 833 | 89% (739)c | 6% (48)c | 6% (46)a | 92% (90–93%) | ||
| Non-Ag | BIRS | 1 | 0% (0) | 100% (1)a,b | 0% (0) | 50% (0–0%) | 0.020 |
| DIRS | 10 | 50% (5)a | 50% (5)b | 0% (0) | 75% (56–94%) | ||
| WIRS | 78 | 63% (49)a | 15% (12)a | 22% (17) | 71% (63–78%) | ||
| Total | BIRS | 81 | 40% (32)a | 58% (47)a | 3% (2)a | 69% (61–76%) | < 0.001 |
| DIRS | 100 | 74% (74)b | 25% (25)b | 1% (1)a | 87% (82–91%) | ||
| WIRS | 911 | 87% (788)c | 7% (60)c | 7% (63)a | 90% (88–91%) |
Each superscript letter denotes a subset of genotype categories whose column proportions do not differ significantly from each other at the 0.05 level. BIRS, before IRS; DIRS (2010), during IRS (2016); WIRS, 4 years after IRS withdrawal (2020); Ag, An. gambaiae s.s. only; Non-Ag, all other An. gambiae s.l. sibling species. †Frequency of the 1014F allele with the 95% confidence interval