Fig. 2.

Alluvial plot with transitions of progression stages. This figure shows the transition between different stages of progression. These are presented in different colours for significant progression, moderate progression, stable, improvement or missing parameters. The frequencies are shown for each follow-up visit (FU) starting with the first follow-up visit (FU 1) after 6 months, FU 2 after 12 months, FU 3 after 18 months, etc