Table 2.
Characteristics of patients with resected, early-stage, EGFR-mutated NSCLCs according to relapse status.
| Characteristic | Without relapse (n = 126, %) | With relapse (n = 45, %) |
|---|---|---|
| Male sex | 49 (38.9) | 20 (44.4) |
| Age, median [range] | 68.3 [40–85] | 69.5 [43–86] |
| Smoking status | ||
| Former and current smokers | 34 (27) | 11 (24.4) |
| Non-smokers | 92 (73.0) | 34 (75.6) |
| Body mass index >30 | 7 (5.6) | 1 (2.2) |
| Symptoms | 33 (26.2) | 16 (35.6) |
| Respiratory | 32 (25.4) | 16 (35.6) |
| Thrombosis | 6 (4.8) | 2 (4.4) |
| Occupational exposure | 11 (8.7) | 5 (11.1) |
| Incidental diagnosis | 78 (61.9) | 21 (46.7) |
| Non-squamous histology | 125 (99.2) | 42 (93.3) |
| PD-L1 status (n = 109) | 74 | 35 |
| 0 | 48 (64.9) | 18 (40) |
| 1–49% | 15 (20.3) | 13 (28.9) |
| ⩾50% | 11 (14.9) | 4 (8.9) |
| EGFR status | ||
| Exon 19 | 49 (38.9) | 15 (33.3) |
| Exon 21 | 46 (36.5) | 17 (37.8) |
| Exon 20 | 16 (12.7) | 8 (17.8) |
| Exon 18 | 6 (4.8) | 5 (11.1) |
| Other exons | 2 (1.6) | - 0/– |
| Co-mutations | 7 (5.6) | - 0/– |
| Wedge | 5 (4) | 1 (2.2) |
| Segmentectomy | 23 (18.3) | 2 (4.4) |
| Lobectomy | 97 (77) | 40 (88.9) |
| Pneumonectomy | 0 | 1 (2.2) |
| Complete lymph node | 122 (96.8) | 42 (93.3) |
| Resection completeness R0 | 124 (98.4) | 41 (91.1) |
| Chemotherapy peri-operative | 14 (11.1) | 15 (33.3) |
| Radiotherapy post-surgery | 5 (4) | 1 (2.2) |
| p Stage | ||
| I | 103 (81.7) | 14 (31.1) |
| II | 11 (8.7) | 13 (28.9) |
| III | 10 (8) | 18 (40) |
EGFR, epidermal growth factor receptor gene; NSCLC, non-small-cell lung cancer; PD-L1, programmed death protein-1 ligand.