Table 2.
Differences in Symptom Severity Scores Between Patients With and Without Chemotherapy-Induced Nausea
| Symptom | Clinically Meaningful Cut-off Scores | No Nausea 52.5% (n = 681) |
Nausea 47.5% (n = 615) |
Statistics |
|---|---|---|---|---|
| Mean (SD) | Mean (SD) | |||
| CES-D score | ≥16.0 | 10.29 (8.56) | 15.65 (10.14) | t = −10.08, p < 0.001 |
| Trait Anxiety Inventory score | ≥32.2 | 33.06 (9.82) | 37.32 (10.69) | t = −7.34, p < 0.001 |
| State Anxiety Inventory score | ≥31.8 | 31.23 (11.07) | 36.66 (13.19) | t = −7.88, p < 0.001 |
| Attentional Function Index score | 6.81 (1.70) | 5.95 (1.80) | t = 8.76, p < 0.001 | |
| >7.5 High | ||||
| General Sleep Disturbance Scale | ≥43.0 | 46.82 (19.19) | 58.50 (19.46) | t = −10.68, p < 0.001 |
| Morning fatigue score (LFS) | ≥3.2 | 2.48 (2.00) | 3.80 (2.30) | t = −10.85, p < 0.001 |
| Evening fatigue score (LFS) | ≥5.6 | 4.89 (2.14) | 5.81 (2.05) | t = −7.80, p < 0.001 |
| Morning energy score (LFS) | ≤6.2 | 4.64 (2.29) | 4.14 (2.18) | t = 3.98, p < 0.001 |
| Evening energy score (LFS) | ≤3.5 | 3.68 (1.96) | 3.40 (2.11) | t = 2.45, p = 0.015 |
| Percentage of patients with pain (%, n) | 49.3 (332) | 64.8 (396) | FE, p < 0.001 |
Abbreviations: CES-D = Center for Epidemiological Studies-Depression Scale, FE = Fisher’s Exact, LFS = Lee Fatigue Scale, SD = standard deviation