Table 5.

Multiple Logistic Regression Analysis Predicting Nausea Group Membership (n = 1035)

Predictor	Odds Ratio	95% CI	p-value
Education (years)	0.93	0.89, 0.98	0.003
Child care responsibilities	1.42	1.03, 1.97	0.032
Karnofsky Performance Status score	0.96	0.95, 0.98	< 0.001
CES-D score	1.03	1.00,1.05	0.026
General Sleep Disturbance Scale score	1.01	1.00,1.02	0.011
Evening fatigue score (LFS)	1.12	1.04,1.20	0.003
Perceived Stress Scale score	0.97	0.95, 0.99	0.015
IES-R Intrusion subscale score	1.35	1.04, 1.75	0.026
CTX cycle length			0.001
21 day cycle vs 14 day cycle	0.58	0.44, 0.77	< 0.001
28 day cycle vs 14 day cycle	0.91	0.52, 1.61	0.754
21 day cycle vs 28 day cycle	0.64	0.37, 1.11	0.110
Antiemetic regimen			0.019
Steroid alone or serotonin receptor antagonist alone vs None	0.88	0.48, 1.61	0.675
Serotonin receptor antagonist and steroid vs None	1.52	0.87, 2.67	0.141
NK-1 receptor antagonist and two other antiemetics vs None	1.37	0.75, 2.49	0.307
Serotonin receptor antagonist and steroid vs Steroid alone or serotonin receptor antagonist alone	1.73	1.21, 2.49	0.003
Steroid alone or serotonin receptor antagonist alone vs NK-1 receptor antagonist and two other antiemetics	0.64	0.42, 0.97	0.037
Serotonin receptor antagonist and steroid vs NK-1 receptor antagonist and two other antiemetics	1.12	0.80, 1.56	0.529
Overall model fit: df = 13, X² = 189.99, p < 0.001

Abbreviations: CES-D = Center for Epidemiological Studies-Depression Scale, CI = confidence interval, CTX = chemotherapy, IES-R = Impact of Event Scale-Revised, LFS = Lee Fatigue Scale, NK-1 = neurokinin-1