Table 2.
Model performance and recommendation effect.
| Model | HR | HRa | dRMST | NNT | C-indexb | IBSb | C-indexc | IBSc |
|---|---|---|---|---|---|---|---|---|
| BITES | 0.53 (0.48–0.60) | 0.65 (0.55–0.78) | 7.92 (7.81–8.15) | 1.67 (1.24–2.41) | 0.55 (0.51–0.58) | 0.05 (0.04–0.07) | 0.62 (0.60–0.63) | 0.08 (0.07–0.09) |
| CMHE | 0.55 (0.49–0.62) | 0.69 (0.58–0.81) | 7.39 (5.62–9.16) | 1.85 (1.34–2.78) | 0.63 (0.62–0.65) | 0.06 (0.04–0.07) | 0.63 (0.63–0.64) | 0.08 (0.07–0.08) |
| DeepSurv | 0.68 (0.62–0.75) | 0.80 (0.68–0.93) | 5.10 (4.98–5.26) | 3.16 (2.28–4.85) | 0.55 (0.52–0.58) | 0.08 (0.06–0.10) | 0.63 (0.62–0.64) | 0.11 (0.10–0.11) |
| CPH | 0.54 (0.48–0.61) | 0.66 (0.56–0.79) | 7.63 (7.50–7.81) | 1.76 (1.28–2.65) | 0.60 (0.57–0.64) | 0.07 (0.06–0.09) | 0.64 (0.63–0.65) | 0.08 (0.07–0.08) |
| ST | 0.94 (0.88–1.01) | 0.96 (0.89–1.03) | 0.83 (0.73–0.95) | 23.51 (9.43–55.56) | 0.53 (0.50–0.56) | 0.12 (0.10–0.14) | 0.54 (0.53–0.55) | 0.15 (0.14–0.16) |
| RSF | 0.58 (0.52–0.64) | 0.66 (0.57–0.77) | 7.13 (5.67–8.97) | 1.97 (1.45–2.90) | 0.58 (0.55–0.63) | 0.08 (0.06–0.09) | 0.62 (0.61–0.63) | 0.09 (0.08–0.09) |
BITES, balanced individual treatment effect for survival data; CMHE, Cox mixtures with heterogeneous effects; CPH, Cox proportional hazards model; ST, survival tree; RSF, random survival forest; HR, hazards ratio; HRa, inverse probability treatment weighting adjusted HR; dRMST, the difference in 5 years restricted mean survival time; NNT, number needed to treat; C-index, concordance index; IBS, integral Brier score; b, the indicator of radiotherapy group; c, the indicator of chemoradiotherapy group. Bolded values indicate the best performance of the model in this metric.